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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENND4C
All Species:
13.03
Human Site:
T1578
Identified Species:
47.78
UniProt:
Q5VZ89
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VZ89
NP_060395.4
1673
186857
T1578
E
T
S
T
L
V
E
T
I
R
Q
S
I
Q
H
Chimpanzee
Pan troglodytes
XP_520506
1889
209618
T1794
E
T
S
T
L
V
E
T
I
R
Q
S
I
Q
H
Rhesus Macaque
Macaca mulatta
XP_001101451
1897
211288
T1802
A
T
S
T
L
V
E
T
I
R
Q
S
I
Q
H
Dog
Lupus familis
XP_852024
1908
212109
T1813
A
T
S
T
L
V
E
T
I
R
Q
S
I
Q
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3U1Y4
1499
164722
K1410
V
G
L
N
E
V
H
K
A
V
G
L
L
L
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424821
1830
204859
N1735
A
T
N
T
L
L
E
N
I
K
L
S
I
Q
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919990
1942
214159
V1847
R
S
L
L
N
S
I
V
R
S
I
Q
M
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.6
85.4
80.4
N.A.
20.7
N.A.
N.A.
N.A.
66.5
N.A.
49.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
82.4
86.1
83.5
N.A.
36.2
N.A.
N.A.
N.A.
75.6
N.A.
62.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
6.6
N.A.
N.A.
N.A.
60
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
13.3
N.A.
N.A.
N.A.
80
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% D
% Glu:
29
0
0
0
15
0
72
0
0
0
0
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
15
0
0
0
0
0
0
0
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
72
% H
% Ile:
0
0
0
0
0
0
15
0
72
0
15
0
72
0
0
% I
% Lys:
0
0
0
0
0
0
0
15
0
15
0
0
0
0
0
% K
% Leu:
0
0
29
15
72
15
0
0
0
0
15
15
15
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% M
% Asn:
0
0
15
15
15
0
0
15
0
0
0
0
0
15
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
58
15
0
72
0
% Q
% Arg:
15
0
0
0
0
0
0
0
15
58
0
0
0
0
0
% R
% Ser:
0
15
58
0
0
15
0
0
0
15
0
72
0
0
0
% S
% Thr:
0
72
0
72
0
0
0
58
0
0
0
0
0
0
0
% T
% Val:
15
0
0
0
0
72
0
15
0
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _